Heazlett replaces fellow batsman Max Bryant in the 13-man squad in the only change to the team humbled by 10 wickets by the Adelaide Strikers yesterday in Adelaide.
The left-hander last played for the Heat against the Melbourne Stars on the Gold Coast earlier this month before he was stricken with illness that saw him briefly hospitalised in Hobart.
He was due to be in action this week for the Queensland Academy of Sport in the Toyota 2nd XI T20 competition on the Sunshine Coast alongside fellow Heat squad mates Cameron Gannon, Jack Prestwidge and Matt Kuhnemann.
The Heat have two key games at the Gabba this week that will shape their chances of making the Finals.
Brisbane play the Renegades followed by the second placed Sydney Sixers on Thursday evening.
Tickets are selling quickly for both matches through Ticketek.
Brisbane Heat v Melbourne Renegades, Gabba, tomorrow 6.10pm Qld time.
50 Chris Lynn (c)
15 Joe Burns
31 Ben Cutting
17 AB de Villiers
4 Sam Heazlett
2 Josh Lalor
55 Ben Laughlin
19 James Pattinson
59 James Peirson
16 Jack Prestwidge
77 Matthew Renshaw
4 Mitch Swepson
7 Mujeeb Ur Rahman